The receiver position remains uncertain in the case of the 49ers with Week 1 drawing closer. Both Brandon Aiyuk and Jauan Jennings are sidelined through injury, and in each case there is no firm timeline for a return. 
Aiyuk continues to rehab the ACL and MCL tears which ended his 2024 campaign. Throughout the offseason, a main question for San Francisco has been his ability to return to full health in time for the start of the season. Aiyuk has been ahead of schedule, but as of last month a stint on the active/PUP list seemed likely in his case. Such a scenario would ensure at least a four-game absence to begin the campaign.
During a Thursday appearance on KNBR radio, 49ers general manager John Lynch said (via Cam Inman of the San Jose Mercury News) he doubts Aiyuk will be able to play in the team’s regular season opener. He confirmed there is still no timetable in place, though, meaning it remains to be seen is an PUP stint will be deemed necessary. Aiyuk has four years remaining on the $30MM-per-year extension he signed last offseason.
Meanwhile, the 49ers continue to wait for Jennings’ return to action. A calf injury has him sidelined against the backdrop of a request for an upgraded contract. Jennings has not officially asked to be traded, per head coach Kyle Shanahan, but a report from last month stated he will seek a change of scenery in the absence of a raise being worked out through an extension. With nothing imminent on that front, Jennings continues to recover.
“Jauan’s working with our health and performance staff, trying to get back out on the field,” Lynch said of the 28-year-old (via David Bonilla of 49ers WebZone). “Jauan got his calf in the offseason, strained it, and calves can kind of linger, unfortunately. And came out, practiced some, and wasn’t feeling great, and so we’ve kind of put him off to the side… Don’t have any timetable, but we’ll see.”
Jennings enjoyed a career year in 2024 as the 49ers dealt with injuries elsewhere on the receiver depth chart. The decision to trade away Deebo Samuel helped set Jennings up for another season in a large offensive role. One year remains on the former seventh-rounder’s contract and he is owed $4MM for 2025. A strong season would help Jennings’ market for next spring, provided no extension is worked out before that point.
2024 first-rounder Ricky Pearsall is in line to serve as a key figure in San Francisco’s passing attack provided he can remain healthy this season. The team also has veteran Demarcus Robinson and recent signing Robbie Chosen in the mix. Aiyuk and Jennings will each be important elements in the 49ers’ efforts to rebound from last year’s performance, but it is still unclear when either of them will be healthy.