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49ers’ Trent Williams Out For Week 18; George Kittle Plans To Play

January 4, 2026 by Pro Football Rumors

5:40PM: As the 49ers prepare to take on the Seahawks for the No. 1 seed in the NFC, they will officially be doing so without Williams. San Francisco listed him as one of their inactive players for tonight’s game.

10:59AM: It appears the 49ers will go without future Hall of Fame left tackle Trent Williams in their pivotal regular-season finale against the Seahawks on Saturday. Williams, who suffered a hamstring injury in a win over the Bears last Sunday, did not practice this week. That suggests he won’t take the field with the NFC West and the No. 1 seed in the conference on the line, Ian Rapoport of NFL Network says.

If Williams sits Saturday, it’ll prevent the 37-year-old from logging his first 17-game campaign. A career-long starter since entering the NFL as a first-round pick (No. 4) with Washington in 2010, Williams has earned his 12th Pro Bowl nod this season. He’s Pro Football Focus’ third-ranked tackle out of 86 qualifiers.

It’s obviously less than ideal for the 49ers to go without Williams, but they pulled off a thrilling 42-38 win in Week 17 despite his absence. Williams played one snap before exiting, leaving Austen Pleasants to take over for the rest of the game. The fourth-year man will make the first start of his career Saturday if Williams is unavailable. It’ll be a tall order against a Seattle defense that ranks second in scoring, fifth in yards and eighth in sacks.

In better news for the 49ers, seven-time Pro Bowl tight end George Kittle said he “absolutely” plans to play in Week 18 (via Nick Wagoner of ESPN). Kittle, a limited participant in practice this week, missed the Chicago game with an ankle issue, continuing an injury-riddled year for him.

After suffering a right hamstring tear in a Week 1 victory in Seattle, Kittle spent over a month on IR. The 32-year-old has appeared in just 10 of 16 games this season, but when healthy enough to play, he has continued to post superb production. Kittle has hauled in 52 of 62 targets for 599 yards and seven touchdowns. Adding in Kittle’s blocking prowess, he’s PFF’s No. 1-ranked tight end among 75 qualifiers.

The 49ers have overcome a slew of notable injuries this year en route to a 12-4 record. While the team remains banged up, there’s only one more hurdle to clear to ensure homefield advantage through the playoffs. If the 49ers complete the season sweep of the Seahawks at home, they won’t go on the road again. That includes the Super Bowl, where the 49ers will host the AFC champion at Levi’s Stadium if they survive the NFC onslaught in January.

Filed Under: 49'ers

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