• Skip to main content
  • Skip to secondary menu
  • Skip to primary sidebar

San Francisco Sports Today

San Francisco Sports News Continuously Updated

  • Baseball
    • A’s
    • Giants
  • Football
    • 49’ers
    • Raiders
  • Basketball
    • Kings
    • Warriers
  • Sharks
  • Earthquakes
  • Colleges
    • San Jose State
    • Stanford
    • University of California, Berkeley

Prediction and betting odds for Bills vs. Chiefs in AFC championship

January 26, 2025 by Niners Wire

The San Francisco 49ers didn’t hold up their end of the bargain for a potential Super Bowl rematch with the Kansas City Chiefs.

While the 49ers stumbled to a 6-11 finish this year, the Chiefs cruised to a 15-2 regular season record, a first-round bye, and another AFC title game appearance. They’ll play host to the Buffalo Bills, who have had their own postseason struggles with Kansas City.

The Chiefs just continue plugging away winning games, even if it isn’t as aesthetically pleasing as it used to be. San Francisco knows first-hand about the Chiefs’ ability to win messy games. So do the Bills. They’ve had more postseason losses to QB Patrick Mahomes and the Chiefs than the 49ers have. The Bills and QB Josh Allen are 0-3 against the Chiefs in the playoffs since their first meeting in the 2020 AFC championship game.

Let’s get to the odds and a prediction:

Bills vs. Chiefs game odds:

All NFL Odds via BetMGM:

  • Point spread: Chiefs -2
  • Money line: Chiefs -130/ Bills +110
  • Over-under: 49

Bills vs. Chiefs injury updates:

  • Bills injury report
    • OUT
      FS Taylor Rapp (back/hip)
    • QUESTIONABLE
      LB Baylon Spector (calf)
      CB Christian Benford (concussion/personal)
  • Chiefs injury report
    • NONE

Bills vs. Chiefs prediction, pick

It’s hard to put much stock into the Bills’ regular season win over Kansas City. However, this may be the year lightning strikes for Buffalo. Their defense should have the tools to at least limit an up-and-down Chiefs offense. Plus, Bills QB Josh Allen may just be playing well enough to overcome a very good Kansas City defense and help Buffalo earn a trip to the Super Bowl.

Prediction: Bills 24, Chiefs 23

Get more betting analysis and predictions at Sportsbook Wire.

Like this article?

Sign up for the Niners Wire email newsletter to get our top stories in your inbox every morning

An error has occured

Please re-enter your email address.

Thanks for signing up!

You’ll now receive the top Niners Wire stories each day directly in your inbox.

Filed Under: 49'ers

Primary Sidebar

Recent Posts

  • How all 30 teams can upgrade at Trade Deadline
  • How all 30 teams can upgrade at Trade Deadline
  • Utah Mammoth re-sign Jack McBain to 4-year contract worth $21.25 million
  • Willy Adames pulls up just in time
  • Weekend Minor League roundup, July 5-6: Marco Luciano is on fire

Categories

  • 49'ers
  • A's
  • Earthquakes
  • Giants
  • Kings
  • Raiders
  • San Jose State
  • Sharks
  • Stanford
  • Uncategorized
  • University of California, Berkeley
  • Warriers

Archives

  • July 2025
  • June 2025
  • May 2025
  • April 2025
  • March 2025
  • February 2025
  • January 2025
  • December 2024
  • November 2024
  • October 2024
  • September 2024
  • August 2024
  • July 2024
  • June 2024
  • May 2024
  • April 2024
  • March 2024
  • February 2024
  • January 2024
  • December 2023
  • November 2023
  • October 2023
  • September 2023
  • August 2023
  • July 2023
  • June 2023
  • May 2023
  • April 2023
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • July 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • November 2021
  • October 2021
  • September 2021
  • August 2021
  • July 2021

Our Partners

All Sports

  • San Francisco Chronicle
  • San Francisco Examiner
  • The Mercury News
  • 247 Sports
  • Bleacher Report
  • Forgotten 5
  • Golden Gate Sports
  • The Sports Fan Journal
  • The Spun
  • USA Today

Baseball

  • San Francisco Giants
  • Oakland A's
  • Last Word On Baseball - Oakland A's
  • Last Word On Baseball - San Francisco Giants
  • MLB Trade Rumors - A's
  • MLB Trade Rumors - Giants
  • White Cleat Beat
  • Around The Foghorn
  • Athletics Nation
  • McCovey Chronicles

Basketball

  • Golden State Warriors
  • Sacramento Kings
  • A Royal Pain
  • Amico Hoops - Kings
  • Amico Hoops - Warriors
  • Blue Man Hoop
  • Golden State Of Mind
  • Hoops Hype - Warriors
  • Hoops Hype - Kings
  • Hoops Rumors - Warriors
  • Hoops Rumors - Kings
  • Lets Go Warriors
  • Last Word On Pro Basketball - Golden State
  • Last Word On Pro Basketball - Sacramento
  • Pro Basketball Talk - Warriors
  • Pro Basketball Talk - Kings
  • Real GM - Warriors
  • Real GM - Kings
  • Sactown Royalty

Football

  • San Francisco 49ers
  • Las Vegas Raiders
  • 49ers Gab
  • Just Blog Baby
  • Last Word On Pro Football
  • NFL Trade Rumors - San Francisco 49ers
  • NFL Trade Rumors - Las Vegas Raiders
  • Niners Nation
  • Niner Noise
  • Niners Wire
  • Our Turf Football
  • Pro Football Rumors - 49ers
  • Pro Football Rumors - Raiders
  • Pro Football Talk - 49ers
  • Pro Football Talk - Raiders
  • Raiders Wire
  • Silver And Black Pride
  • Total 49ers

Hockey

  • Blades Of Teal
  • Fear The Fin
  • Last Word On Hockey
  • Pro Hockey Rumors
  • Pro Hockey Talk
  • The Hockey Writers

Soccer

  • Center Line Soccer
  • Last Word on Soccer
  • MLS Multiplex

College

  • Busting Brackets
  • California Golden Blogs
  • College Sports Madness
  • College Football News
  • Rule Of Tree
  • Saturday Blitz
  • The Daily Californian
  • The Stanford Daily
  • Zags Blog

Copyright © 2025 · Magazine Pro on Genesis Framework · WordPress · Log in