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San Francisco 49ers vs. Los Angeles Rams odds, tips and betting trends | Week 4

September 28, 2022 by Niners Wire

San Francisco (1-2) will face off against their NFC West rival, the Los Angeles Rams (2-1) in a matchup on Monday, October 3, 2022 at Levi’s Stadium. The spread foreshadows a close game, with the 49ers favored to win by 1.5 points. The over/under for the contest is 42 points.

The 49ers lost against the Denver Broncos in their last game, 11-10.

Niners quarterback Jimmy Garoppolo went 18-for-29 for 211 yards, with one TD and one INT, against the Broncos.

The Rams won against the Arizona Cardinals in their last game, 20-12.

Find out how to watch this matchup on TV in the article below.

49ers vs Rams Betting Information

NFL odds courtesy of Tipico Sportsbook. Odds updated Wednesday at 8:47 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread Favorite: San Francisco (-1.5)
  • Moneyline: San Francisco (-122), Los Angeles (+102)
  • Total: 42 Points

OFFER: Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

49ers Betting Info

  • San Francisco was 4-4 overall, and 4-4 against the spread, at home last season.
  • The 49ers have covered the spread one time this season (1-2-0).
  • As 1.5-point favorites or greater at home last year, San Francisco was 3-4 ATS.
  • The 49ers have an ATS record of 1-2 when playing as at least 1.5-point favorites.
  • Last season, San Francisco went over the total in four of eight games at home.
  • Games involving the 49ers have yet to hit the over this season.

49ers Leaders

  • Jeff Wilson Jr.: 39 CAR / 181 YDS / 60.3 YPG / 0 TD / 7 REC / 58 YDS / 19.3 YPG / 0 TD
  • Deebo Samuel: 17 CAR / 111 YDS / 37 YPG / 1 TD / 12 REC / 131 YDS / 43.7 YPG / 0 TD
  • Brandon Aiyuk: 10 REC / 142 YDS / 47.3 YPG / 1 TD
  • Jauan Jennings: 6 REC / 71 YDS / 23.7 YPG / 0 TD

Place your legal, online sports bets in CO and NJ at Tipico Sportsbook now.

49ers vs Rams Game Info

  • Game Day: Monday, October 3, 2022
  • Game Time: 8:15 PM ET
  • Location: Santa Clara, California
  • Stadium: Levi’s Stadium
  • TV Channel: ESPN
  • Live Stream: fuboTV (Watch for free)

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

Filed Under: 49'ers

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